Ultra-Processed Foods and Depression

Dr. Stacy Livingston

Recent research findings have drawn attention to a connection between ultra-processed foods, particularly artificial sweeteners, and an increased risk of depression. Here's a comprehensive look into what this means for our diets and overall well-being.

The Evidence

A study in the U.S. has linked the consumption of large amounts of ultra-processed foods, especially beverages with artificial sweeteners, to a higher risk of developing depression. While the negative physical impacts of these foods, such as strokes, heart attacks, and raised blood pressure, have long been recognized, this marks a notable shift in understanding the relationship between diet and mental health.

Key Findings:

The study utilized data from a significant longitudinal research project on women's health in the U.S.Over a span of 14 years, diets and mental health of more than 30,000 primarily white middle-aged women were monitored.

The risk of depression increased by 49% in women consuming nine or more portions of ultra-processed foods daily when compared to those consuming fewer than four portions.

Profiling Ultra-Processed Foods

Although processing is common in our food supply, ultra-processed foods are defined by their high levels of additives, chemicals, and substances not typically used in home cooking. Examples include packaged snacks, frozen meals, high-fructose corn syrup, and hydrogenated oils. These foods have already been tied to severe health conditions, including obesity, cancer, and diabetes.

Ultra-processed foods contain ingredients such as protein isolates, chemical additives, and high-fructose corn syrup.

They are associated with a slew of health issues and are notoriously high in calories, fat, salt, and sugar.

Both Forbes and Medical News Today emphasize the study's finding that artificial sweeteners and artificially sweetened drinks particularly increase the risk of depression. Responding to the data, Professor Andrew T Chan from Massachusetts General Hospital noted that the research accounted for dietary habits before the onset of depression, reinforcing the potential causal link between diet and depression.

Diverse Opinions and Perspectives

The findings have evoked a mix of responses. While some experts, such as Keith Frayn from the University of Oxford, underscore the relationship between artificial sweeteners and depression, others are more cautious. 

Further Insights

Medical News Today contributes additional insights into the study. The research incorporated the Nurses' Health Study II participants and applied the NOVA classification to identify and categorize ultra-processed foods. The artificial sweeteners present in ultra-processed foods emerged as a significant concern. Dietitian Jessie Hulsey emphasizes the broader implications of this association, noting the importance of whole, unprocessed foods for physical and mental well-being.

Limitations and Future Directions

However, like all studies, this research isn't without its limitations:

  • The sample population was predominantly non-Hispanic white women.
  • There's an inherent reliance on self-reported data.
  • The study does not conclusively prove causation between ultra-processed foods and depression.

Future studies may dive deeper into understanding the underlying mechanisms linking depression and ultra-processed food consumption, especially focusing on artificial sweeteners.

Moving Forward: Tips for a Healthier Diet

There's increasing evidence suggesting health benefits from reducing ultra-processed food consumption. Strategies to achieve this include:

  • Prioritizing whole foods such as fruits, vegetables, whole grains, and lean meat.
  • Reading food labels diligently.
  • Opting for smaller portions.
  • Consulting nutrition specialists for personalized advice.


The emerging connection between ultra-processed foods and depression underscores the holistic impact of our dietary choices. It's more crucial than ever to prioritize nutrition and make informed food decisions.



The Guardian

Medical News Today

JAMA Network

Dr. Livingston enjoys taking care of patients from the mild to the wild. He is the doctor for you, if you have been to other places and told there was nothing that could be done for your or told “It’s all in your head”. He accepts all types of cases including workers compensation, auto accident and personal injury cases. He believes chiropractic can help everyone add life to their years and get them back to doing what they love.

No items found.
Nth Degree - Safari Dan
Next Up In
Nth Degree - Safari Dan
Pinnacle Chiropractic (Mid)
Banner for Certainty Tools, Play your Game.  Blue gradient color with CertaintyU Logo
No items found.
Nth Degree - Safari Dan
Pinnacle Chiropractic (Mid)